130414-1258 EDT
To be on the safe side the answer would be no.
Most of these transient limiters are some sort of soft knee varistor. Try to find a curve of voltage vs current for the one in which you are interested. Are these of value yes. Are there better ways possibly.
Many electronic circuits won't tolerate much over-voltage, and not for very long, possibly just milliseconds.
To really protect what is in a house takes many different things at the entry point, and distributed thru the house. At each important load point a back-to-back Zener diode pair (Transorb is one trade name) with a threshold somewhat above the maximum normal expected peak voltage would be useful, with some series impedance before the limiter. Zener diodes have a very sharp knee, MOVs do not.
Then do many things at the house entry bulkhead. Once there was a good discussion on the Internet about this by a radio amateur, but this disappeared a number of years ago. A large copper plate was the bulkhead, feed thru capacitors were in the bulkhead, a wide copper sheet ran from the bulkhead to the ground rod system (to reduce high frequency impedance), and various transient limiters. This provided very good lightning protection.
The bad neutral problem could be solved with shunt SCRs, Zener diode triggers, and fast blow fuses that the SCRs overloaded by a crowbar function.
Also you do not want additional grounding electrodes in the house.
To do a good job is not inexpensive.
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