110115-2228 EST
kwired:
It is probably a good idea to have twisted pair speaker wires, but I doubt the noise is entering the system at this point.
Speakers are relatively low impedance and narrow band devices. Unless transformers are used the impedance level is probably below 16 ohms.
There are other high impedance and high sensitivity components that are more likely the entry point of the noise. In particular microphone circuits.
Your comment about CBers getting into an audio system probably points to something in the amplifier at a sensitive point acting as a detector of the high frequency signal. You could take a small loop of wire, a solid state diode, small capacitor, and earphones and go near a broadcast station, detect, and listen to their broadcast.
There have been reports that being near very high power AM stations, WLW at 500,000 watts, would cause some bed springs or other metallic components of neighbors to demodulate the broadcast and produce acoustic output.
There are ham radio operators with 1 KW of output power that when pointing their beam antenna at a neighbor's house would light close lights.
Power level, and existence of detection devices at points of high sensitivity, will be the determining factor in the effect of noise.
Microphone circuits may be 100,000 ohms or more for input impedance, and sensitive to millivolt levels. Good radios will have input sensitivities in the microvolt range but lower impedance than microphone inputs.
.