Depends. The NEC has something to say if it's Class 1 wiring but not CL3 or 2. But I wouldn't even consider that. I always follow the Chapter 3 fill requirements for both the conduit and boxes depending on the wire size when running TFFN or THWN. If you are pulling cables (that will never be Class 1) you need to consult the manufacturer of the cable for the recommended conduit fill. It's usually 40% based in the OD of the cable. But you still size your boxes according to the wire size, number and chapter 1.
-Hal