I would run a conduit home run to a J-box them MC from there.
Have you considered how labor intensive running all MC home runs would be vs conduit? Not to mention an ugly mess.
I never allowed my electricians run MC home runs, unless special conditions or permission.
Under special conditions we would use Home Run MC cable....but it's very expensive
If you have any doubts, wheel that run off using conduit home run/MC...then wheel it off using all MC
In fact, do that and tell us the results
Here is a fine example of how this move to no shared neutrals makes things more costly than they should be.
Back in the day I could run a 1/2" emt, pull nine HRs and branch out from there. Now I have to run two pipes or run one oversized pipe with oversized conductors because of derating.
As much as I am a fan of conduit for HRs I'm sure I could install three runs of 12/2/2 for less total cost.
If you don't think too good, don't think too much.
Thats a good point so NOW with no shared neutrals and 6 1P 20a ckts it's a 1" pipe with 6 hots 6 neutrals and 1G or like you said, (3) 12/2/2's MC cable HR. Only thing is spec always says we have to pipe out of panel so I'd run a 10' stick up and out of closet to box.
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