You must have at least one of the electrodes listed in 250.52, and you must have an effective fault path (intentional 250.118) to source if a short to frame occurs. This happens while not creating a parallel neutral path to source.
See 250.32 and remember neutral current travels all paths to its source - according to each level of resistance - so you must contain neutral current on an intended conductor only never frames and earth. This is why 250.24(A)(5) and 250.142(B) exist.