Which brings up a good point. It isn't so much the fact that the cable is Series 59 as it is the construction of the cable that is the issue. CATV needs 100% shielding from the headend to the premise device. So much of the Series 59 cable that is out there is older, copper-braid cable, most of which has 85% shielding at best. I've seen some as low as 65%. The cable used MUST have a layer of foil BONDED to the dielectric plus a braid.
Just as important as the cable itself is the connectorization of the cable. If a connector is loose, corroded, plain old junk, or not made up properly, ingress can occur. The return path is more susceptible to ingress than is the forward path. We used to be able to see ingress in pictures in the form of multiple images on locals, herringbone, and other forms of interference on certain channels. Now, with many systems going digital, the channel (say, ESPN) that is on analog channel 20 is now one of the channels digitally modulated to NTSC channel 112 (112-4). If the settop box is mapped so that when the sub goes to channel 20 (as indicated by the display), the STB tunes to NTSC channel 112-4 and he watches ESPN. The interference that he would have normally be seen on channel 20 will not be seen on 112-4.
But, the return path will suffer regardless.
Now, if there's a levels issue in the outside plant, that's another story...