Re: Clean Room Design
If I remember correctly, a class 1000 clean room has no more than 1000 particles larger than 0.5 microns per cubic foot of air (there are class 100, class 10 or even class 1 clean rooms, so I suppose a class 1000 is no big deal in the whole scheme of things.
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Many moons ago, I did some work on the design and construction of a class 10 clean room. First of all, we tried to locate anything that could generate particulates outside the clean room if possible (for instance, instead of putting a process pump and motor inside the clean room, we'd route the process piping outside and put the pump there, so any oil from bearings, carbon from motor brushes, etc. would not be a problem.)
Secondly, anything going inside the clean room must be made of materials that won't generate particulates. Generally, that ended up meaning a good grade of stainless steel; galvanized steel may flake off little bits of galvanizing, some plastic and vinyl products may outgas, and the people running the clean room may even be afraid of things made of anodized aluminum.
Third, all materials and equipment (including tools) needs to be thoroughly cleaned before it is brought into the clean room, and the installation has to be done with care. Everything gets wiped down with solvent and lintfree rags. The electricians may need to wear protective clothing when they're inside the room - if not an entire bunny suit, they still may need to have on hairnets and booties even during early stages of the construction. Things like cutting conduit or stripping wire need to be done outside the clean room if possible. If there's any cutting or sawing inside the room, it has to be done very carefully and with a HEPA vacuum cleaner right there to pick up any saw filings or bits of wire and insulation.