I would say that if you are changing-out an existing panel, you would not be required to use AFCI breakers on the existing circuits, but can't speak for your inspector's interpretation. Any applicable new home runs would need AFCI. Existing multi-wire branch circuits can be AFCI protected using a 2-pole AFCI breaker, but for new ones you could run 14-2-2 or 12-2-2. When you say "total" house rewire, I would say that you are not using the old wiring and yes you would need AFCI. Note: I live in the backward state of Virginia, which is still on the 2005 NEC, so my AFCI experience is limited to bedrooms at this point, but somebody that lives in "the present" might be able to answer the question more accurately!:grin: