My last answer didn't look clear after I read it.
On units with a CFM rating of 2,000 or more. One duct detector on the supply duct. On units greater than 15,000 cfm, duct detectors are required on both the supply and the return.
Local inspectors often modify this requirement. The most common is weather they want the device to report as an alarm or as a supervisory. Supervisory signals are usually local. Thats because DD's are prone to false alarm more than usual.