But it is still up to the AHJ, unless the manufacturer included actual penetration (i.e. knockouts). For example, what if the installer device to mount a 2" listed hub, but cut the hole using a 'sawsall', and it was more oval than round.
It is not a UL issue as long as whatever is installed in the holes meets or exceeds the UL rating of the panel. IOW, if the conduit fitting is rated as type 12, you can install it (assuming you follow the directions properly) in a type 12 enclosure without the enclsoure rating being compromised.
This is what UL says about industrial control enclosures.
The basic standard used to investigate products in this category is UL 508A, "Industrial Control Panels."
According to UL508a:
19 Enclosure Openings
19.1 All openings provided for conduit connections in the field shall be of standard dimensions. When
provided, conduit fittings shall comply with the Standard for Conduit, Tubing, and Cable Fittings, UL 514B.
For enclosures other than Type 1, as noted in column 1 of Table 19.1, the conduit openings and fittings
shall additionally comply with the requirements specified in column 2 of Table 19.1.
So you would not be able to make a hole that was not a standard size.
Tables 19.1 (conduit fittings) and 19.2 (other devices) tell you what rating of devices can be installed in holes.
These tables have two columns - "Enclosure type" and "Openings are able to be closed by equipment marked".
For example - a type 3R enclosure can have holes closed by devices marked 3, 3R, 3RX, 3S, 3SX, 3X, 4, 4X, 6, 6P, Wet Location, or Raintight.
19.3 Openings provided in enclosures for mounting components shall be covered with components
intended for such mounting. For an enclosure type specified in column 1 of Table 19.2, openings provided
for components, including ventilation openings, or observation windows, shall be closed with components
that have been evaluated for one of the enclosure Types in column 2 of Table 19.2.
Table 19.3 has alternate ratings of enclsoures based on installing devices through the enclsoure that have a lesser rating. For instance a type 4X enclosure that has 3RX, 3SX, 3X, 4X devices mounted through it becomes a type 3RX. In this case a drain has to be added and there has to be a locking mechanism available.