The only time a neutral is required to be run is for grounded services and it has to be brought to the service equipment disconnecting means, 250.24(C). If a neutral is not needed in panels downstream of this point it is not required.
(C) Grounded Conductor Brought to Service Equip-
ment.
Where an ac system operating at 1000 volts or less is
grounded at any point, the grounded conductor(s) shall be
routed with the ungrounded conductors to each service dis-
connecting means and shall be connected to each discon-
necting means grounded conductor(s) terminal or bus. A
main bonding jumper shall connect the grounded conduc-
tor(s) to each service disconnecting means enclosure. The
grounded conductor(s) shall be installed in accordance with
250.24(C)(1) through (C)(4).