Re: replacing old 2 conductor receptacles
With the GFCI recpt, the breaker back at the panel would trip on ordinary overload or L/N short. The GFCI device only trips when it detects ~5ma leakage/imbalance between L/N. In theory, if you were standing on something dry and well insulated and stuck a paper clip into the GFCI, there may not be enough to cause a trip.
I don't see a need for a seperate IG bar back at the main panel - that as far back as you'd normally go with the IG's anyway. They are allowed to "pass through" other panels along the way back to the main without connection.