Re: romex parallel to floor joist
I think if I were an electrician I would consider a few different things. First, I would not secure to the bottom flange for fear of a drywaller missing the flange and nailing my wire. Second, I would staple in the web and perhaps tweak the ends of the staple with a pair of needlenose to make them less subject to withdrawl. Third, I would stay away from the pre-drilled holes so that if the plumber (or other) needs to use them they would not have to re-route my wires.
Remember that the NEC simply states that they must be secured at 4.5 feet. The manner in which you do it is your business, so I wouldn't lose much sleep over it.