130926-1041 EDT
Your question is not clear.
If you have a 100 A load 1000 ft from your source, 2000 ft of wire, and use 0000 copper and the wire is at 20 C, then the voltage drop is about 10 V. Because of self heating of the wire from the current this 10 V drop may be a good estimate for your 800 ft. A 10 V drop from 48 V puts your load at 38 V. This does not look good.
What is the 100 ft you mentioned.
You may need to consider a different way to get 48 V DC at your end point.
What is the load? Is this on continuously or just for short times? More information is needed.
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