I have always run power from more than one phase or leg if you prefer and never had any problems, as long as a few conditions were observed:
- Run dedicated neutrals for each circuit used for the audio equipment;
- Connect ALL of the "source" (before the power amps) equipment to the same phase/leg;
- Try to distribute the amplifier loads equally amongst the phases/legs; and
- Observe good audio wiring techniques, especially use of "telescoping" shields.
Isolated grounds are not necessary in most applications as long as you use good audio wiring practice and the EGC wiring is properly sized and bonded as per Code.
The dedicated neutrals are a must. I know that some will say they're not necessary, but 20+ years of experience and over 700 screens wired tell me otherwise. I will not try to argue the physics of why, other than to state that it avoids any possibility, no matter how slight, of harmonics getting into the rack.
Telescoping shields means that the shield of the audio line is connected at one end only. In my specific application, that means from the Cinema Processor (source) to the power amps, the shields are connected at the amps end only. Most of the lines into the Cinema processor are connected shields at the Cinema processor end only.
For most other audio installations, try connecting the shields at the switcher or processor end only first. You may have to reverse and connect at the source equipment end only, or sometimes even at both ends.
I think it was already mentioned here, but bears repeating:
Do not, ever, lift the equipment's power cord/line ground!!
You're not solving the hum problem that way, just creating a potentially fatal hazard!