These circuits are all 120V. Basically they are all circuits coming from a power panel, so each circuit has a hot and a nuetral. Therefore 10 circuits each having a hot and nuetral will have 20 wires. All circuit conductors are #12 and there is only one EGC run with all of these circuits. I'm not sure what you mean by MWBC?
You're about to find out.
If the panel is single-phase, and unless there's a very good reason not to, pair up hots so your 10 circuits could be run on 5 MWBC's; i.e., 5 groups of 2 hots and a shared neutral (which technically is required in order for the grounded conductors to legitimately be called neutrals.)
Now you'd have the figure of 10 conductors to insert into your derating and conduit-sizing equations instead of 20. The shared neutrals ("Is there another kind?" ~ Col. Jessup in A Few Good Men) need not be counted for CCC count. Conduit fill, they still must be considered.
If the panel is 3-phase, the same applies except for 3 hot wires instead of 2 per neutral. That would give you 3 MWBC's plus a single 2-wire circuit, for a count of 11. Since 9 is the 'magic number' which still allows 20a OCP for #12, would it be convenient to run the 10th circuit separately?
The other options are to run two conduits, or place a sub-panel (Bob: :wink

central to the loads (like near where you'd place the J-box) if construction permits. Of course, you'd have to price doing it both ways, and decide whether it's even worth considering with the building layout.
There is obviously a reason you're using the J-box rather than running the circuits to the panel. What is that reason? That's where I'd start.