Most of my work is residential design-build.
I also do some small commercial design-build stuff.
What kind of risk and exposure are you anticipating?
I usually like it because the designer and contractor are one. And I have a good rapport with the people I work for. I'm usually involved with design if it's tricky, and I'm trusted enough to make some changes without asking.
But the biggest problems have always come when there's not a certain plan before beginning. I try to stay away from those kinds of contractors because they'll ask for a bid from you with a completely uncertain scope of work, then they try to act like your price is all-inclusive regardless of changes or additions.
Those dysfunctional types always have more change orders, they always create the least happy customers, and never can keep subs