I just looked up some loading values, from a post 2016 transformer design. These units likely have lower core losses than previous designs.
For a 45kVA 480:208Y/120 the core losses are about 180W and at 100% load the conductor losses are about 1770W, so for a 45kVA load its losses are roughly 1,950W.
For an equivalent 75kVA the core losses are about 253W and at 100% load the conductor losses are about 2518W, so for a 45kVA (60%) load its losses are roughly 1,160W.
All things equal, for a continuous load (which is rare), it may make sense to purchase an oversized transformer just looking at operating expense.
DOE 2016 requirements are in effect.
the difference in core losses alone are 73 watts. that's 1752 wh per day, 63.94 kwh per year. around here expect to pay about $0.14 per kwh. result for one year.... $89.52 additional cost for the 75kva.
however it is as you say, there are two components to the heat losses. core losses (above) and copper losses. 45kva will dissipate more (copper loss) heat in a 45 kva transformer than 45 kva through a 75 kva. this is because the 45kva will get hotter-as it does the equivalent impedance rises.
the resulting additional energy cost of the 45 kva operated at 45 kva and assuming $0.14 per kwh, is $748.10 above the cost of 75 kva operated at 45. that additional cost to operate the 45 will slide toward the $89.52 as the continuous load decreases.
if im the owner, and there is space, i want the 75 kva.
energy costs vary widely by state. hawaii average cost per kwh is $0.34. an owner there might be more sensitive to the subject.