160809-2144 EDT
Johnnybob:
I will have, for instance, +24DC and -24DC, +15DC and -15DC, +5DC and -5DC I'm pretty sure the neg side of these power supplies can't be tied together and grounded,
By +24DC and -24DC do you mean there is 48 V difference between the two terminals? I doubt it. Most likely this means 24 V between the two terminals and + and - define polarity. If this is simply a 24 V DC supply, and internally the supply is isolated from EGC, earth, chassis, or any other power supply, then either terminal could be tied to any desired reference point, including 1,000,000 V above earth if there were no voltage breakdown problems.
Continuing this thought: any one terminal of any one of the power supplies can be connected to any desired reference point so long as the connected loads are not interconnected in such a way that would produce a conflict.
In systems that I build I typically have +24 V, +16 V, -16 V, +12 V, -12 V, +8 V, and +5 V. Sometimes a -5 V. Each of these is referenced to a common that in turn is connected to the equipment chassis (possibly a 20,000 # machine), and that to the EGC.
+12 is derived from +16 via a series pass regulator. Same for the others. Combinatorial logic is powered from +5 V and Common, Operational amplifiers from +/-!2 V. Relays from +24 and Common. RS232 uses +/-12 V. RS232 signal output is referenced to Common at both ends of the communication path. But these are two different commons and there is likely an EGC voltage drop between the commons.
RS232 without isolation on its interconnection cable has serious problems from EGC noise and fault currents. The least significant problems are data errors. Large voltages like 80 V or more from fault currents can destroy RS232 components and possibly damage futher into the electronic equipment.
.